Bus Tickets from Florence, SC, US to Durham, NC, US

Find affordable bus tickets from Florence, SC, US to Durham, NC, US with flexible options. Book your trip now

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TodaySep 11
TomorrowSep 12
SatSep 13
SunSep 14
MonSep 15
from US$33
TueSep 16
WedSep 17
ThuSep 18

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: September 15 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: September 15 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: September 15 at
    Departure city: Florence
    Departure location: 2301 W Lucas St.
    Arrival time: September 15 at
    Destination city: Durham
    Destination location: BP Gas Station
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Florence
    Departure location: 2301 W Lucas St.
    Arrival time: September 16 at
    Destination city: Durham
    Destination location: BP Gas Station
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: September 15 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: September 15 at
    Destination city: Durham
    Destination location: Durham Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from Florence to Durham

Bus
Average PriceUS$33 - US$81Average Duration3h 30m
5kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$47 - US$70Average Duration7h 7m
20kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Florence to Durham

Among the sustainable travel choices, the bus stands out as a good way to reach Durham. The journey takes about 3 hours 30 minutes, and with fares starting at just US$33, it presents an excellent value for a comfortable ride.

3bus per day
3h 30mAverage Duration
US$33Cheapest ticket
5kgCO₂ emissions

Bus Florence, SC, US to Durham, NC, US: Trip Overview

Average Ticket PriceUS$67
Average Bus Trip Duration3h 30m
Number of daily buses3
Earliest bus departure12:05am
Distance216 km
Latest bus departure9:00pm

Florence to Durham Bus

With Busbud, comparing and booking tickets for a bus from Florence to Durham is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Durham.

Whether it is cheap bus tickets or more luxurious buses going to Durham from Florence, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Florence, SC, US - Durham, NC, US

  1. How far is Florence from Durham?

    It's about 210 km (131 miles) from Florence to Durham.

  2. What are the departure and arrival locations for buses traveling from Florence to Durham?

    Buses departing from Florence Bus Station in Florence will take you to Durham Greyhound Bus Station in Durham.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-09
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09-10
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Today
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09-12
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09-15
US$25
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busbud logoThe cheapest trip from Florence, SC, US to Durham, NC, US was searched and found on Sep 15, 2025 with a price of US$25

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to Durham, NC, US, as early as possible.

You can expect to pay from US$25 to US$60 for a bus ticket from Florence, SC, US to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$25 which is on 2025-09-15.

Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Florence to Durham.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Durham.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Florence to Durham.

Tune out to the fine sounds of your best music playlist on your bus trip from Florence to Durham while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Florence, SC, US by bus?

Bus from Durham, NC, US to Florence, SC, US

You can also go to Durham, NC, US by train

Train from Florence, SC, US to Durham, NC, US

Why choose Busbud?

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