Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Eugene (U of O - Jaqua Academic Ctr) | Greyhound Bus Stop | CheapestFastest | |||||
 | Amtrak Station | Santa Fe Depot | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Eugene (U of O - Jaqua Academic Ctr) | San Diego (Old Town-FlixBus) | No tags | |||||
| Amtrak Station | Santa Fe Depot | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Eugene (U of O - Jaqua Academic Ctr) | UCSD Health La Jolla Station | No tags |
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Compare 2 ways to go from Eugene to San Diego
Busbud recommends taking the train from Eugene to San DiegoAmong the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 1 day, 7 hours 35 minutes, and with fares starting at just US$179, it presents an excellent value for a comfortable ride.
Bus Eugene to San Diego, CA, US: Trip Overview
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Eugene to San Diego Bus
Busbud helps you find a bus from Eugene to San Diego. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Eugene to San Diego from the most reliable bus companies operating this trip.
Discover how much the bus trip from Eugene to San Diego will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Eugene and San Diego?
Frequently asked questions on the trip Eugene - San Diego, CA, US
What is the travel distance from Eugene to San Diego?
It's about 1364 km (846 miles) from Eugene to San Diego.
What are the departure and arrival locations for buses traveling from Eugene to San Diego?
Buses departing from 5th Street Market in Eugene will take you to Mission Valley Sheraton in San Diego.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Eugene to San Diego, CA, US was searched and found on Aug 20, 2025 with a price of US$313To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Eugene to San Diego, CA, US, as early as possible.
You can expect to pay from US$313 to US$1,184 for a bus ticket from Eugene to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$313 which is on 2025-08-24.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Eugene and San Diego!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Eugene to San Diego, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Eugene to San Diego will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Eugene to San Diego while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from Eugene to San Diego, CA, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
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Popular Buses Connecting Eugene
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