Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Des Moines (Subway) | Charlotte (Freedom Dr) | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Charlotte Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Charlotte (Freedom Dr) | No tags | ||||
FlixBus + Greyhound | Bus | Des Moines (Subway) | Charlotte Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Des Moines (Subway) | Charlotte Bus Station | No tags |
Get from Des Moines to Charlotte
The journey takes about 1 day, 10 hours 30 minutes, and with fares starting at just $195, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Charlotte?
Stops in Des Moines
Stops in Charlotte
- A
Tornado & El Expreso Bus Company
4705 N. Tryon S, Charlotte, NC, USA - C
Charlotte Greyhound Bus Station
601 W Trade St , Charlotte, NC 28202 - D
Agencia El Salvador Bus Stop
4335 N Tryon St, Charlotte, NC 28213 - E
4127 Glenwood Dr
4127 Glenwood Dr, Charlotte, NC 28208 (Exxon Gas Station)
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $195
Frequently asked questions about travelling from Des Moines to Charlotte, NC by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Charlotte?
The cheapest bus tickets from Des Moines to Charlotte start from $195. The average price for this route is around $322. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Charlotte?
The average bus travel time from Des Moines to Charlotte is 1d 10h, covering a distance of 1317 km. The quickest bus can get you there in 1d 5h and is operated by Greyhound.
Which bus companies service the Des Moines to Charlotte route?
Several major bus companies operate on this route with 4 buses available per day.
What are the earliest and latest departure times for the bus from Des Moines to Charlotte?
The earliest bus departs from Des Moines to Charlotte at 5:30am. And the latest bus departs at 9:45am.
What are the CO₂ emissions for the bus trip from Des Moines to Charlotte?
A bus trip from Des Moines to Charlotte generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Charlotte, NC was searched and found on Jan 10, 2026 with a price of $184To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Charlotte, NC, as early as possible.
You can expect to pay from $184 to $184 for a bus ticket from Des Moines to Charlotte, NC based on the last 2 days. You can expect to find the cheapest price for the trip at $184 which is on 2026-01-10.
