Bus Tickets from Denver to Indianapolis

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TodaySep 2
TomorrowSep 3
from US$151
ThuSep 4
FriSep 5
from US$135
SatSep 6
from US$166
SunSep 7
MonSep 8
from US$131
TueSep 9

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: September 3 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 4 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: September 3 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Northeast
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Denver to Indianapolis

Bus
Average PriceUS$111 - US$446Average Duration1d 9h
40kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$162 - US$373Average Duration1d 2h
146kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Denver to Indianapolis

Among the sustainable travel choices, the train stands out as a good way to reach Indianapolis. The journey takes about 1 day, 2 hours 50 minutes, and with fares starting at just US$162, it presents an excellent value for a comfortable ride.

1train per day
1d 2hAverage Duration
US$162Cheapest ticket
146kgCO₂ emissions

Bus Denver to Indianapolis: Trip Overview

Average Ticket PriceUS$163
Average Bus Trip Duration1d 9h
Number of daily buses5
Earliest bus departure7:50am
Distance1608 km
Latest bus departure8:10pm

Denver to Indianapolis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Denver to Indianapolis.

We make sure you can find a bus service from Denver to Indianapolis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Denver to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Denver - Indianapolis

  1. What is the distance between Denver and Indianapolis?

    The distance between Denver and Indianapolis is around 1609 km (998 miles).

  2. What are the departure and arrival locations for buses traveling from Denver to Indianapolis?

    Buses traveling this route start their trip at Union Station, in Denver, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$203
09-01
US$111
Today
US$118
09-03
US$143
09-04
US$148
09-05
US$127
09-06
US$158
09-07
No data
busbud logoThe cheapest trip from Denver to Indianapolis was searched and found on Sep 1, 2025 with a price of US$111

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Indianapolis, as early as possible.

You can expect to pay from US$111 to US$311 for a bus ticket from Denver to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$127 which is on 2025-09-05.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Denver to Indianapolis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Denver to Indianapolis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Denver to Indianapolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Denver to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Denver to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Denver by bus?

Bus from Indianapolis to Denver

You can also go to Indianapolis by train

Train from Denver to Indianapolis

Why choose Busbud?

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