Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal de Cartagena | Terminal del Norte | Cheapest | |||||
| Terminal de Cartagena | Terminal del Norte | Fastest | |||||
| Terminal de Cartagena | Terminal del Norte | No tags | |||||
 | Terminal de Cartagena | Medellin North Bus Terminal | No tags | |||||
Unitransco + Expreso Brasilia | Terminal de Cartagena | Medellin North Bus Terminal | No tags |
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Bus Cartagena, CO to Medellin: Trip Overview
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Cartagena to Medellin Bus
Busbud helps you find a bus from Cartagena to Medellin. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Cartagena to Medellin will be provided by the most trusted bus companies.
Whether it is cheap bus tickets or more luxurious buses going to Medellin from Cartagena, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Cartagena and Medellin?
Frequently asked questions on the trip Cartagena, CO - Medellin
What is the travel distance from Cartagena to Medellin?
It's about 465 km (288 miles) from Cartagena to Medellin.
What are the departure and arrival locations for buses traveling from Cartagena to Medellin?
Buses traveling this route start their trip at Terminal de Cartagena, in Cartagena, and end it at Terminal del Norte, in Medellin.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cartagena, CO to Medellin was searched and found on Sep 19, 2025 with a price of US$38To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cartagena, CO to Medellin, as early as possible.
You can expect to pay from US$38 to US$51 for a bus ticket from Cartagena, CO to Medellin based on the last 2 days. You can expect to find the cheapest price for the trip at US$38 which is on 2025-09-19.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Cartagena and Medellin!
Much more than a mere vehicle taking you from Cartagena to Medellin, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Cartagena to Medellin.
Make a music playlist for your bus ride from Cartagena to Medellin, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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Popular Buses Connecting Cartagena
Buses Leaving from Cartagena
- Bus from Cartagena to Tolú
- Bus Cartagena - Cali
- Cartagena - Cúcuta
- Bus from Cartagena to Montería
- Bus Cartagena - Fundacion
- Cartagena - Bogotá
- Bus from Cartagena to Covenas
- Bus Cartagena - Valledupar
- Cartagena - San Onofre
- Bus from Cartagena to Mompós
- Bus Cartagena - Caucasia
- Cartagena - Lorica
- Bus from Cartagena to Riohacha
- Bus Cartagena - Buritaca
- Cartagena - San Gil
Buses Going to Cartagena
- Bus from Bogotá to Cartagena
- Bus Montería - Cartagena
- Honda - Cartagena
- Bus from Valledupar to Cartagena
- Bus Sincelejo - Cartagena
- Socorro - Cartagena
- Bus from Cali to Cartagena
- Bus Fundacion - Cartagena
- Riohacha - Cartagena
- Bus from San Gil to Cartagena
- Bus Aguachica - Cartagena
- Cúcuta - Cartagena
- Bus from Lorica to Cartagena
- Bus Tolú - Cartagena
- Maicao - Cartagena
Popular Buses Connecting Medellin
Buses Leaving from Medellin
- Bus from Medellin to Montería
- Bus Medellin - Bucaramanga
- Medellin - Manizales
- Bus from Medellin to Coveñas
- Bus Medellin - Covenas
- Medellin - Caucasia
- Bus from Medellin to Armenia
- Bus Medellin - Santa Fe de Antioquia
- Medellin - Cúcuta
- Bus from Medellin to Tolú
- Bus Medellin - Barranquilla
- Medellin - Timana
- Bus from Medellin to Mocoa
- Bus Medellin - San Onofre
- Medellin - Ipiales
Buses Going to Medellin
- Bus from Cali to Medellin
- Bus Montería - Medellin
- Ibagué - Medellin
- Bus from Bucaramanga to Medellin
- Bus Manizales - Medellin
- Pereira - Medellin
- Bus from Guatape to Medellin
- Bus Santa Marta - Medellin
- Barranquilla - Medellin
- Bus from Cúcuta to Medellin
- Bus Armenia - Medellin
- Buga - Medellin
- Bus from Pasto to Medellin
- Bus Chigorodó - Medellin
- San Jerónimo - Medellin
Popular routes in this country
- Bus from Medellin to Jardin
- Bus Cartagena - Medellin
- Medellin - Guatape
- Bus from Bogotá to Villa de Leyva
- Bus Medellin - Santa Marta
- Bogotá - Cali
- Bus from Medellin to Pereira
- Bus Bogotá - San Gil
- Cartagena - Palomino
- Bus from Santa Marta to Palomino
- Bus Maicao - Bogotá
- Bogotá - Pereira
- Bus from Jardin to Medellin
- Bus Barranquilla - Cartagena
- Pitalito - Armenia